ID literature review

2019 - 3rd Quarter

Original Research Articles*

July 2019

CRP guided antibiotic use in copd exacerbation

C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations (NEJM 7/2019) ARTICLE & EDITORIAL 

  • CRP testing to guide antibiotic prescribing for COPD exacerbations resulted in lower antibiotic use without evidence for harm

REcombinant zoster vaccine after stem cell transplant

Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial (JAMA 7/2019) ARTICLE

  • Recombinant zoster vaccine (2 dose course) reduced the incidence of herpes zoster following autologous hematopoietic stem cell transplantation

Mortality from meningitis in Botswana

Mortality in adult patients with culture-positive and culture-negative meningitis in the Botswana national meningitis survey: a prevalent cohort study (Lancet Infectious Diseases 7/2019) ARTICLE & EDITORIAL 

  • Almost half of adult patients with pneumococcal, tuberculous, and culture-negative meningitis in Botswana died within 1 year of lumbar puncture

causes of severe pneumonia in children from africa and asia

Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study (Lancet 7/2019) ARTICLE & EDITORIAL 

  • Viruses were estimated to cause around 61% of cases of severe pneumonia in children < 5 years old, with bacteria causing around 27%, and Mycobacterium tuberculosis causing around 6%

August 2019

September 2019

Disclosures at the time of publication for all articles: None